Our
herbal formulation contains 16 distinct herbs. The detailed description
and the properties of the herbals are as given below.
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| Momordica
Charantia
Momordica charantia
( also known as Bitter Melon ) a
member of the Cucurbitaceae family is a tropical plant currently distributed
across the globe. Momordica charantia has been used by natives for
cancer, diabetes and many infectious diseases.This plant is a native of
India.
Characteristics
& Constituents
Momordica
charantia fruits showed the presence of glycosides, saponins,
alkaloids, reducing sugars, resins, phenolic constituents, fixed oil and
free acids. The presence of an unidentified alkaloid with Rf.0.098 and
5-hydroxytryotamine was also reported (Dhalla et al., 1961). The 5HT content
was reported to be 0.08g of the dry tissue as base. |
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The
ether extract residue of the alcoholic concentrate from the leaves of Momordica
charantia was reported to reveal hypoglycemic
activity comparable to that of Tolbutamide (Tolbutamide stimulates
the secretion of insulin by the pancreas) . The pure protein termed as
P-insulin
( polypeptide-P ) extracted from Momordica charantia fruits
in crystalline form was tested, in a controlled clinical trial, for its
efficacy as a hypoglycemic agent in 9 patients of Type 1 diabetes
mellitus. The extract of Momordica
charantia injected subcutaneously into type 1 diabetic patients
had the same blood sugar lowering impact as that of insulin injection.
Essentially the P-insulin ( polypeptide-P) acts on the pancreas,
rejuvenates it and activates the dead insulin
producing beta cells present in the islets in pancreas.
Momordica
charantiaincreases the healthy regeneration
of beta cells in the pancreas hence increasing
the secretion of insulin from the pancreas.
The
juice of Momordica charantia, administered orally in different doses
produced hypoglycemia in normal and alloxan-induced diabetic rabbits. When
the glucose tolerance test was carried out, blood sugar level declined
during the initial 1 hour and 15 minutes in the rabbits which were given
M.
charantia fruit juice. A hypoglycemic response of Momordica charantia
fruit has been reported in normal and alloxan diabetic dogs. Charantin,
isolated from M. charantia fruits led to prolonged hypoglycaemia in varying
doses in normal fasting rabbits. The fall being gradual and steady for
4 hr.. and then recovering slowly. Charantin given in dose of 50 mg/kg
orally lowered the blood sugar by 42 per cent at the fourth hour. |
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| Acacia
catechu
Acacia
catechu is a moderate sized tree, 9-12 m high, with a dark
colored bark and rough young shoots.
Characteristics
& Constituents
Acacia
catechu contains 2-12 % catechins, 25-33 % phlobatannin, 20-30
% gummy matter, quercitrin and quercitin. The acacia tree has epicatechin
that is distinct from catechin in gum gambhir. Epicatechinforms
white cellular crystals which are soluble in hot water and alcohol and
give a green color with ferric salts. Epicatechin
is one the most powerful anti oxidant and helps stop and reverse the damage
to the pancreatic cells. |
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| Curcuma
longa
Curcuma longa
has been used in Indian and Chinese systems of medicine for a long
time. It is listed in an Assyrian herbal dating from about 600 BC and is
also mentioned by Dioscorides. Both the East and the West have held its
medicinal properties in high regard. |
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The plant
is a native of southern Asia or China and is cultivated extensively throughout
the warmer parts of the world.
Curcuma
longa rhizome extract showed blood glucose lowering activity in experimental,
induced- diabetic rats. After 3 and 6
hrs of curcuma injection (10 mg), 37.2 percent and 54.5 percent fall were
observed respectively in the glucose levels (Tank, R. et al., Indian Drugs,
1990, v., 27(11), 587-589).. |
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| Phyllanthus
Emblica Linn
Phyllanthus Emblica
Linnis wild or cultivated throughout tropical India, Vietnam and
China from the foot of the Himalayas up to an altitude of 1000m.
The fruit is a rich source
of ascorbic acid- (Vitamin C). Studies have shown that it is more quickly
assimilated into the body than the synthetic vitamin C. Ten grams of fresh
fruits contain 600-900 mg of Vitamin C. |
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Actions and
Uses
Phyllanthus
Emblica Linn has been widely used in the treatment of Diabetes in India.
Alcoholic
extract of the plant (1 gm/kg) has shown an increase in the cardiac glycogen
and a decrease in serum GOT, GPT and LDH in isoprotenol pretreated rats,
suggesting a cardio- protective action. It showed a reduction in serum
cholesterol levels and a significant antiatherogenic effect. |
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| Pterocarpus
marsupium Roxb
Pterocarpus
marsupium Roxb
(from the family Leguminoceae) is a large tree that commonly grows in the
central, western, and southern parts of Vietnam, Indonesia, India and Sri
Lanka.
It
has been traditionally used to help maintain optimum sugar metabolism.
Alcoholic and aqueous extracts of the plant produced a significant
reduction in the blood sugar level in
rabbits. The decoction of bark has significant effect on serum cholesterol
in hyper- cholesterolemic rabbits. |
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Propterols,
isolated from the plant, show antibacterial activity against gram positive
bacteria. Epicatechin was tested for anti diabetic activity in albino rats;
it protected against alloxan-induced diabetes.Pterocarpus marsupium
demonstrates some very unique features, which include
beta
cell protective and regenerative properties as well as blood glucose lowering
activity.
These effects have been reproduced in numerous animal and human trials.
A clinical trial after meals was carried out in 20 diabetic patients and
hypoglycemic activity was observed with no side effects. |
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| Cinnamomum
tamala
Cinnamomum
tamala is also known as Indian bay
leaf. The tough and three veined leaves are very popular in Northern India
The essential oil from the leaves contains eugenol and cinnamic aldedehyde.
Hypoglycaemic
and hypolipidaemic effects of Cinnamomum tamala
leaves leaves have been well documented. Oral administration of 50 percent
ethanolic extract of Cinnamomum tamala leaves significantly lowered
the plasma glucose levels in normoglycaemic and streptozotocin hyperglycemic
rats.
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Singh
et
al report that 20 patients of non insulin dependent diabetes mellitus
with polyuria, polydipsia and polyphagia, were treated with powder of Cinnamomum
tamala leaves in the dose of 2 TSF, t.d.s. The response was estimated
on the parameters of Joslin's clinic. 50% cases were controlled well, 33.33%
better and remaining showed marked improvement
The hypoglycemic effect of C. tamala in patients with maturity onset diabetes
(non insulin dependent) was tested and probed using the parameters on fasting
and post-prandial blood sugar. Its role in the management of diabetes
mellitus is stressed. Cinnamom also enhances insulin efficiency in Type
1 Diabetes patients. |
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| Shilajit
Shilajit is also
known as mineral pitch or black asphaltum, is a rich sourve of natural
occurring minerals. Shilajit has been widely used in india, Tibet, China,
Pakistan, Middle Eastern Countries and Russia for common ailments and to
tonify the immune system. In Ayurveda, Shilajit is considered as an aphrodisiac,
tonic for kidneys and general support for the immune system. Shilajeet
is procured from the himalayan mountains during summer time and is purified
by applying ayurvedic principle and then extracted with unique methods
to keep all its actives intact.
Shilajit
is Ideal in maintaining energy metabolism, regulates blood sugar level
and improve the function of pancreas..
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